Zipchip
CE Mass Spectrometry
908 Devices ZipChip® is the new alternative to Liquid chromatography-mass spectrometry (LC-MS). Based on cutting-edge microfluidic technology it integrates capillary electrophoresis and electrospray ionization into an easy to use system that simply replaces your mass spec’s normal source.
The ZipChip® platform prepares and separates a wide range of biological samples, then electrosprays them into your mass spec for analysis. Just clip it on. The process takes as little as three minutes, and results in better separation quality than most LCs in a fraction of the time. Simple workflows and multiple kit options cover a host of biotherapeutic, metabolomic and proteomic applications.
Zipchip Technology
Microfluidic technology integrates capillary electrophoresis (CE) and electrospray ionization (ESI) on the ZipChip. Junctions and dead volumes don’t exist so analytical quality stays high, and no injection bias ups repeatability.
Pick an application, a chip and a kit. After that just two steps: Load the premixed background electrolyte and sample into the autosampler. Pop in a ZipChip and hit run. Use vials or 96-well plates. It’s hands-off from there. Smart chips tell the system which method to use based on your preferences. Samples are automatically loaded, separated and electrosprayed. Integrated software cues the mass spec to start analysis.
Pick an application, a chip and a kit. After that just two steps: Load the premixed background electrolyte and sample into the autosampler. Pop in a ZipChip and hit run. Use vials or 96-well plates. It’s hands-off from there. Smart chips tell the system which method to use based on your preferences. Samples are automatically loaded, separated and electrosprayed. Integrated software cues the mass spec to start analysis.
Simple workflow
1. Pick a BGE Kit
Background electrolyte (BGE) and sample diluent reduce preparation time for your samples. With Zipchip you just dilute and shoot!
- Charge Variant Analysis Kit
- Native Antibody Assay kit
- Intact Antibodies Assay Kit
- Peptide Assay kit
- Metabolites Assay kit
- Oligonucleotides Kit
2. Pick a Chip
With Zipchip you just dilute and shoot! Choose from a range of chip options to optimize your workflow.
- High Speed Chip (HS)
- High Speed Native Chip (HSN)
- High Speed Bare Glass Chip (HSB)
- High Resolution Chip (HR)
- High Resolution Native Chip (HRN)
- High Resolution Bare Glass Chip (HRB)
Zipchip collaborates seamlessly with existing mass spectrometry in the market
High resolution fast separationsNo method development
High tolerant with tough matrixNo need to remove detergents or desalt
Handle wide ranges of sample typesRun small and large molecules
Compatible with market leading MSSeamlessly collaborates with other devices
