The Ultra-high-definition CT (U-CT) system is high-speed (5 s total body mouse) and can scan with ultra-low X-ray radiation doses, down to less than 2 mGy whole-body. By default, both mice and rats can be imaged. Optionally, the system can be upgraded to image medium size animals, enabling whole-body rabbit imaging. Four performance levels ensure a system configuration that can be adapted to the user’s needs. These four performance levels are; Standard E-Class CTSD with reconstructed voxel resolution down to 30 μm, High-Resolution U-CTHR subsystem with reconstructed voxel resolution down to 10 μm, Ultra-High Resolution U-CTUHR subsystem with reconstructed voxel resolution down to 4 μm, and Extra-Ultra-High Resolution U-CTXUHR subsystem with reconstructed voxel resolution down to 2.4 μm using a dedicated ex vivo sample holder.

Optimized for in vivo imaging, the U-CT system features advanced diagnostic capabilities including dynamic contrast-enhanced CT imaging using single- or dual-energy scans, ultra-fast fluoroscopic imaging with up to 66 frames per second, DEXA scanning, virtual endoscopy, and cardiac and respiratory gating – sensor-free if desired for simultaneous multi-animal imaging.