The inVision is a powerful optoacoustic imaging system for small animal imaging. It acquires cross-sectional images, with high resolution, in vivo and in real time. It features stage-controlled translation, repeatable animal positioning and automated time points/intervals. The unique capability of inVision imaging systems is to visualize and quantify optoacoustic contrast throughout the whole animal, from head to tail, without any manual intervention.

The inVision features an increased angular coverage of 310°, with new ring illumination and detector, as well as state-of-the-art algorithms for tomographic image reconstruction, broadband signal detection and spectral analysis. Together with its high-energy 20 Hz pulsed laser system, the inVision provides best-in-class image quality and unrivaled sensitivity.

Besides the in-chamber imaging of small animals, the inVision features options of handheld imaging (for larger animals or tissue samples), in real-time 2D and 3D mode.
Technical specification of detectors:

• 2D: 4MHz, 256 elements, >65% bandwidth
• 3D: 8MHz, 256 elements, >65% bandwidth

• Represents absorbance
• Blood as main component
• Versatile contrast agents

• “Classic” ultrasound
• Whole-body view
• Tomographic quality

• Measures speed of sound
• Indicates tissue stiffness
• Unique new information

• High sensitivity (nmol)
• Real-time image visualisation at video rate
• Volumetric deep-tissue imaging (whole-body penetration in small animal imaging applications)
• Single and multi-wavelength imaging at video rate
• Data post-processing suite for spectral and temporal analysis
• Ultrasound detector array with 64–512 channels
• Tomographic ultrasound

• Cancer - Analyse parameters of disease progression across a wide range of biological mechanisms
• Cardiovascular - Monitoring blood flow and the beating heart in real time
• Brain - High-resolution imaging of deep brain structures, through intact skin and skull
• Kinetics and Biodistribution - Quantify kinetic processes in real time

• Safe animal handling
• Repeatable fixed position
(key for longitudinal studies)
• Easy mounting of animal in holder
• Integrated anesthesia supply

• X-sectional scan along the region of interest
• System calibration before scan
• Fully automated image acquisition (OA and US)
• Access for catheter or thermometer
• Maintains animal body temperature

• Quantitative image reconstruction
• Spectral analysis of chromophores
• Visualization and super-positioning
of OA and US images
• Data and image export