iThera MSOT – Multispectral Optoacoustic Tomography

Multispectral Optoacoustic Tomography (Photoacoustics) utilizes pulsed light at multiple wavelengths and detection of acoustic responses. Images are generated and spectrally unmixed to yield the biodistribution of reporter molecules and tissue biomarkers.

MSOT offers the unique ability to accurately visualize, track and quantify endogenous chromophores, nanoparticles, biomarkers and optical agents, in vivo and in real time. Excellent intrinsic tissue contrast by combining the molecular specificity of optical imaging with the penetration depth and 3D resolution of ultrasound. Offering the best of the Optical and Ultrasound Imaging.

Key benefits of MSOT

  • High sensitivity (nmol)
  • Real-time image visualisation at video rate
  • Volumetric deep-tissue imaging (whole-body penetration in small animal imaging applications)
  • Single and multi-wavelength imaging at video rate
  • Data post-processing suite for spectral and temporal analysis
  • Ultrasound detector array with 64–512 channels
  • Tomographic ultrasound

MSOT Applications

Cancer - Analyse parameters of disease progression across a wide range of biological mechanisms. Cardiovascular - Monitoring blood flow and the beating heart in real time. Brain - High-resolution imaging of deep brain structures, through intact skin and skull. Kinetics and Biodistribution - Quantify kinetic processes in real time.

iThera OPUS – Ultrasound tomography

iThera Medical proudly announces the launch of its integrated optoacoustic ultrasound tomography (OPUS) imaging technology. The MSOT inVision 512-echo provides unparalleled image quality, in real time, throughout the entire animal cross-section.

The integration of reflection-mode ultrasound adds complementary anatomical information, particularly for structures that are poorly perfused.